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Publications

2023

  • Becker F, Fuchs S, Refisch L, Drepper F, Bildl W, Schulte U, Sho Liang S, Heinicke J, Hansen S, -Kreutz C, Warscheid B, Fakler B, Mymrikov E, Hunte C (2023) Conformational regulation and target-myristoyl switch of calcineurin B homologous protein 3, eLife 12:e83868. https://doi.org/10.7554/eLife.83868
  • Denkhaus L, Siffert F & Einsle O (2023) An unusual active site architecture in cytochrome c nitrite reductase NrfA-1 from Geobacter metallireducens. FEMS Microbiol Lett, 370, fnad068.
  • Fischer S, Bürgi J, Gabay-Maskit S, Maier R, Mastalski T, Yifrach E, Obarska-Kosinska A, Rudowitz M, Erdmann R, Platta HW, Wilmanns M, Schuldiner M, Zalckvar E, Oeljeklaus S, Drepper F, Warscheid (2023) Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes.  B. Biol Chem. 2022 Sep 21. doi: 10.1515/hsz-2022-0168.
  • Hua L, Kaiser M, Carabadjac I, Meister A, Hause G, Heerklotz H. Vesicle budding caused by lysolipid-induced asymmetry stress. (2023) Biophys J. 2023 Aug 29:S0006-3495(23)00554-4. doi: 10.1016/j.bpj.2023.08.023.
  • Ilcu L, Denkhaus L, Brausemann A et al. (2023) Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun 14, 5190. https://doi.org/10.1038/s41467-023-40881-y.
  • Kägi, J., Sloan, W., Schimpf, J., Nasiri, H.R., Lashley, D. and Friedrich, T. (2023) Exploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. Sci. Rep., 13, 12226. 10.1038/s41598-023-39430-w.
  • Makarchuk, I., Gerasimova, T., Kägi, J., Wohlwend, D., Melin, F., Friedrich, T. and Hellwig, P. (2023) Mutating the environment of heme b595 of E. coli cytochrome bd-I oxidase shifts its redox potential by 200 mV without inactivating the enzyme. Bioelectrochemistry, 151, 108379. 10.1016/j.bioelechem.2023.108379.
  • Öztürk Y, Andrei A, Blaby-Haas CE, Daum N, Daldal F, Koch HG (2023) Metabolic sensing of extracytoplasmic copper availability via translational control by a nascent exported protein. mBio 14(1): e3040-22 doi: 10.1128/mbio.03040-22.
  • Sarmah P, Shang W, Origi A, Licheva M, Kraft C, Ulbrich M, Lichtenberg E, Wilde A, Koch HG (2023) mRNA targeting eliminates the need for the signal recognition particle during membrane protein insertion in bacteria. Cell reports 42(3):112140 doi: 10.1016/j.celrep.2023.112140.
  • Steigenberger J, Verleysen Y, Geudens N, Madder A, Martins JC, Heerklotz H. (2023) Complex electrostatic effects on the selectivity of membrane-permeabilizing cyclic lipopeptides. Biophys J.  Mar 21;122(6):950-963. doi: 10.1016/j.bpj.2022.07.033.
  • Strotmann, L., Harter, C., Gerasimova, T., Ritter, K., Jessen, H.J., Wohlwend, D. and Friedrich, T. (2023) H2O2 selectively damages the binuclear iron-sulfur cluster N1b of respiratory complex I. Sci. Rep., 13, 7652. 10.1038/s41598-023-34821-5.
  • Yu C, Runge HFP, Mukhopadhyay A, Zolles G, Ulbrich MH. γ-2 and GSG1L bind with comparable affinities to the tetrameric GluA1 core. Cell Mol Biol Lett. 2023 Jul 10;28(1):54. doi: 10.1186/s11658-023-00470-9. PMID: 37430208; PMCID: PMC10332039.

2022

  • Czech L, Mais CN, Sarmah P, Krazat H, Giammarinaro P, Freibert S, Musial J, Bernningshausen O, Steinchen W, Beckmann R., Koch HG and Bange G (2022). Shutdown of secretory pathway by the bacterial alarmones (p)ppGpp. Nature communications, 13:1069 doi: 10.1038/s41467-022-28675-0.
  • Gao M, Moumbock AFA, Qaseem A, Xu Q, Günther S (2022)  CovPDB: a high-resolution coverage of the covalent protein-ligand interactome. Nucleic Acids Res.  Jan 7; 50(D1):D445-D450. doi: 10.1093/nar/gkab868. PMID: 34581813; PMCID: PMC8728183.
  • Hoeser, F., Tausend, H., Götz, S., Wohlwend, D., Einsle, O., Günther, S. and Friedrich, T. (2022) Respiratory complex I with charge symmetry in the membrane arm pumps protons. Proc. Natl. Acad. Sci., https://doi.org/10.1073/pnas.2123090119
  • Hoeser, F., Tausend, H., Götz, S., Wohlwend, D., Einsle, O., Günther, S. and Friedrich, T. (2022) Respiratory complex I with charge symmetry in the membrane arm pumps protons. Proc. Natl. Acad. Sci., 119, e2123090119. https://doi.org/10.1073/pnas.2123090119
  • Hoeser, F., Weiß, M. and Friedrich, T. (2022) The clinically relevant triple mutation in the mtND1 gene inactivates Escherichia coli complex I. FEBS Lett., 596, 1124-1132. https://doi.org/10.1002/1873-3468.14325
  • Kägi, J., Makarchuk, I., Wohlwend, D., Melin, F., Friedrich, T. and Hellwig, P. (2022) E. coli cytochrome bd-I requires Asp58 in the CydB subunit for catalytic activity. FEBS Lett., 596, 2418-2424. https://doi: 10.1002/1873-3468.14482
  • Müller, C., Zhang, L., Zipfel, S. et al. Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature (2022). https://doi.org/10.1038/s41586-022-05015-2
  • Steigenberger J, Mergen C, De Roo V, Geudens N, Martins JC, Heerklotz H. (2022) The effect of membrane thickness on the membrane permeabilizing activity of the cyclic lipopeptide tolaasin II. Front Mol Biosci.  Dec 23;9:1064742. doi: 10.3389/fmolb.2022.1064742.
  • Van den Bergh, B., Schramke, H., Michiels, J., Kimkes, T., Radzikowski, J., Schimpf, J., Vedelaar, S., Burschel, S., Dewachter, L., Loncar, N., Schmidt, A., Meijer, T., Fauvart, M., Friedrich, T., Michiels, J. and Heinemann, M. (2022) Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis. Nat. Commun., 13:54. https://doi.org/10.1038/s41467-022-28141-x
  • Walter C, Marad A and Meisinger C (2022): Monitoring checkpoints of metabolism and protein biogenesis in mitochondria by Phos-tag technology. Journal of Proteomics, 252, 10 Feb, https://doi.org/10.1016/j.jprot.2021.10443.

 

Publication Award 2022: Christoph Müller

2021

  • Andrei A, di Renzo AM, Öztürk Y, Meisner A, Daum N, Frank F, Rauch J, Daldal F, Andrade S and Koch HG (2021). The CopA2-type P1B –type ATPase CcoI serves as central hub for cbb3-Cox biogenesis. Frontiers in Microbiology 12,712465; doi: 10.3389/fmicb.2021.712465
  • Brandel A, Aigal S, Lagies S, Schlimpert M, Meléndez AV, Xu M, Lehmann A, Hummel D, Fisch D, Madl J, Eierhoff T, Kammerer B, Römer W (2021) The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa. Cell Mol Life Sci. 2021 Feb 8. DOI: 10.1007/s00018-021-03766-1.
  • Brausemann A, Zhang L, Ilcu L & Einsle O (2021) Architecture of the membrane-bound cytochrome c heme lyase CcmF. Nat Chem Biol, 17, 800-805.
  • Cechova K, Lan C, Macik M, Barthes NPF, Jung M, Ulbrich (2021) MH Kappa but not delta or mu opioid receptors form homodimers at low membrane densities. Cellular and Molecular Life Sciences 78: 7557-7568.
  • Dannenmaier S, Desroches Altamirano C, Schüler L, Zhang Y, Hummel J, Milanov M, Oeljeklaus S, Koch HG, Rospert S, Alberti S, Warscheid B. (2021) Quantitative proteomics identifies the universally conserved ATPase Ola1p as a positive regulator of heat shock response in Saccharomyces cerevisiae. J Biol Chem.  Sep 24:101050. doi: 10.1016/j.jbc.2021.101050. Epub ahead of print. PMID: 34571008.
  • Frensch M, Jäger C, Müller PF, Tadić A, Wilhelm I, Wehrum S, Diedrich B, Fischer B,  (2021) Bacterial lectin BambL acts as a B cell superantigen. Cell. Mol. Life Sci. 78, 8165–8186. doi.org/10.1007/s00018-021-04009-z.
  • Lan C, Stulz A, Barthes NPF, Lauw S, Salavei P, Jung M, Heerklotz H, Ulbrich MH. (2021) Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties. Nanoscale,  doi.org/10.1039/d1nr06574b.
  • Lohner  P, Zmyslia M, Thurn J., Pape J, Gerasimaite R, Keller-Findeisen J, Groeer S, Deuringer B, Süss R, Walther A, Hell S, Lukinavicius G, Hugel T, Jessen-Trefzer  C (2021) Inside a Shell – Organometallic Catalysis Inside Encapsulin Nanoreactors. Angewandte Chemie. DOI: 10.1002/ange.202110327.
  • Moumbock AFA, Li J, Tran HTT, Hinkelmann R, Lamy E, Jessen HJ, Günther S (2021) ePharmaLib: A Versatile Library of e-Pharmacophores to Address Small-Molecule (Poly-)Pharmacology. J Chem Inf Model. Jul 26;61(7):3659-3666. doi: 10.1021/acs.jcim.1c00135. Epub 2021 Jul 8. PMID: 34236848.
  • Nuber F, Merono L, Oppermann S, Schimpf  J, Wohlwend D and Friedrich T (2021) A quinol anion as catalytic intermediate coupling proton translocation with electron transfer in E. coli respiratory complex I. Front. Chem., 9, 672969. DOI: 10.3389/fchem.2021.672969.
  • Nuber F, Schimpf J, di Rago J-P, Tribouillard-Tanvier D, Procaccio V, Martin-Negrier M-L, Trimouille A, Biner O, von Ballmoos C and Friedrich T (2021) Biochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I. Sci. Rep., 11, 12641. DOI: 10.1038/s41598-021-91631-3.
  • Öztürk Y, Blaby-Haas CE, Daum N, Andrei A, Daldal F and Koch HG (2021) Maturation of Rhodobacter capsulatus Multicopper Oxidase CutO Depends on the CopA Copper Efflux Pathway and requires the cutF Product. Frontiers in Microbiology 12:720644; doi: 10.3389/fmicb.2021.720644.
  • Olerinyova A, Sonn-Segev A, Gault J, Eichmann,C, Schimpf J, Kopf AH, Rudden LSP, Ashkinadze D, Bomba R, Frey L, Greenwald J, Degiacomi MT,  Steinhilper R, Killian A, Friedrich T, Riek R, Struwe WB, Kukura P (2021) Mass Photometry of Membrane Proteins. Chem 7, 1-13. DOI 10.1016/j.chempr.2020.11.011.
  • Omidvar R, Yareni A, Brandel A, Hasenclever L, Helmstädter M, Rohrbach A, Römer W, Madl J (2021). Quantification of nanoscale forces in lectin-mediated bacterial attachment and uptake into giant liposomes. Nanoscale. DOI 10.1039/D0NR07726G.
  • Oswald J, Njenga R, Natriashvili A, Sarmah P and Koch HG (2021) The dynamic Sec translocon. Frontiers Mol. Biosciences 8, 664241; doi: 10.3389/fmolb.2021.664241
  • Siukstaite L, Rosato F, Mitrovic A, Müller PF, Kraus K, Notova S, Imberty A, Römer W (2021) The Two Sweet Sides of Janus Lectin Drive Crosslinking of Liposomes to Cancer Cells and Material Uptake. Toxins 13(11):792. doi.org/10.3390/toxins13110792.
  • Steigenberger J, Verleysen Y, Geudens N, Martins JC, Heerklotz H. (2021)The Optimal Lipid Chain Length of a Membrane-Permeabilizing Lipopeptide Results From the Balance of Membrane Partitioning and Local Damage. Front Microbiol. 2021 Sep 14;12:669709. doi: 10.3389/fmicb.2021.669709.
  • Walter C, Marada A, Suhm T, et al. (2021) Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery. Nature Communications. Jul;12(1):4284. DOI: 10.1038/s41467-021-24426-9. PMID: 34257281; PMCID: PMC8277783.

 

Publication Award 2021: Franziska Nuber

2020

  • Andrei A, Öztürk Y, Khalfaoui-Hassani B, Rauch J, Marckmann D, Trasnea P-I, Daldal F, Koch H-G. (2020) Cu Homeostasis in Bacteria: The Ins and Outs. Membranes, 10(9):242.

  • Bernhardt M, Berman S, Zechel D, Bechthold A (2020) Role of Two Exceptional Trans Adenylation Domains and MbtH-like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A From Streptomyces Calvus ATCC 13382. Chembiochem, Online ahead of print. DOI 10.1002/cbic.202000142.

  • Dannenmaier S, Oeljeklaus S and Warscheid B (accepted for publication). 2nSILAC for quantitative proteomics of prototrophic baker's yeast. Methods Mol Biol.

  • Darkow E, Rog-Zielinska E A, Madl J, Brandel A, Siukstaite L, Omidvar R, Kohl P, Ravens U, Römer W, Peyronnet R (2020) The Lectin LecA Sensitizes the Human Stretch-Activated Channel TREK-1 but Not Piezo1 and Binds Selectively to Cardiac Non-myocytes. Frontiers in Physiology 21, 457, DOI=10.3389/fphys.2020.00457.

  • Kaiser J, Castellano M, Gnandt D, Koslowski T (2020) Monte Carlo simulation and thermodynamic integration applied to protein charge transfer. J Com Chem 41, 1105-1115. DOI 10.1002/jcc.26155.

  • Liang S, Fuchs S, Mymrikov EV, et al. (2020) Calcium affects CHP1 and CHP2 conformation and their interaction with sodium/proton exchanger 1. FASEB J 34:3253-3266. DOI 10.1096/fj.201902093R.

  • Lill P, Hansen T, Wendscheck D, Klink BU, Jeziorek T, Vismpas D, Miehling J, Bender J, Schummer A, Drepper F, Girzalsky W, Warscheid B, Erdmann R, Gatsogiannis C (2020) Towards the molecular architecture of the peroxisomal receptor docking complex; Proc Natl Acad Sci U S A, accepted for publication.

  • Markones M*, Fippel A*, Kaiser M, Drechsler C, Hunte C and Heerklotz H (2020) Stair-way to Asymmetry: Five steps to lipid-asymmetric proteoliposomes. Biophys J 3495, 34343-3434 (*equal contribution).

  • Mühlbauer M, Saura P, Nuber F, Di Luca A, Friedrich T, Kaila V (accepted for publication) Water-Gated Proton Transfer Dynamics in Respiratory Complex I.J. Am. Chem. Soc.142, 13718-13728; DOI: 10.1021/jacs.0c02789.

  • Nikolaev A, Makarchuk I, Thesseling A, Hoeser J, Friedrich T, Melin F and Hellwig P (2020) Stabilization of the highly hydrophobic membrane protein cytochrome bd oxidase on metallic surfaces for direct electrochemical studies. Molecules, 25, 3240; DOI:10.3390/molecules25143240.

  • Poveda-Huertes D, Matic M, Marada A, Habernig L, Licheva M, Myketin L, Gilsbach R, Tosal-Castano S, Papinski D, Mulica P, Kretz O, Kücükkose C, Taskin A A, Hein L, Kraft C, Büttner S, Vögtle FN, & Meisinger C (2020) An Early mtUPR: Redistribution of the Nuclear Transcription Factor Rox1 to Mitochondria Protects against Intramitochondrial Proteotoxic Aggregates. Mol Cell 77, 180-188.

  • Regenold M, Steigenberger J, Siniscalchi E, Dunne M, Casettari L, Heerklotz H, Allen C (2020): Determining critical parameters that in uence in vitro performance characteristics of a thermosensitive liposome formulation of vinorelbine, Journal of Controlled Release, 328, 551-561, https://doi.org/10.1016/j.jconrel.2020.08.059.

  • Santos Seica AF, Schimpf J, Friedrich T and Hellwig P (2020) Visualizing the movement of the amphipathic helix in the respiratory complex I using a nitrile infrared probe and SEIRAS. FEBS Lett594, 491-496. DOI 10.1002/1873-3468.13620.

  • Schubert T, Sych T, Madl J, Xu M, Omidvar R, Patalag L J, Ries A, Kettelhoit K, Brandel A, Mely Y, Steinem C, Werz D B, Thuenauer R, Römer W (2020) Differential recognition of lipid domains by two Gb3-binding lectins. Sci Rep 10, 9752.  https://doi.org/10.1038/s41598-020-66522-8.  

  • Schummer A, Maier R, Gabay-Maskit S, Hansen T, Mühlhäuser WWD, Suppanz I, Fadel A, Schuldiner M, Girzalsky W, Oeljeklaus S, Zalckvar E, Erdmann R (2020) Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in Saccharomyces cerevisiae. Front. Cell Dev. Biol, https://doi.org/10.1101/2020.07.03.186833.

  • Schwarzer P, Tsypik O, Zuo C, Alali A, Wunsch-Palasis J, Heitzler T, Derochefort J, Bernhardt M, Yan X, Paululat T, Bechthold A (2020) Early Steps in the Biosynthetic Pathway of Rishirilide B. Molecules 25, E1955. DOI 10.3390/molecules25081955.

  • Sonn-Segev A, Belacic K, Bodrug T, Young G, VanderLinden R, Schulman B, Schimpf J, Friedrich T, Dip P, Schwartz T, Bauer B, Peters JM, Struwe W, Benesch J, Brown N, Haselbach D, Kukura P (2020) Quantifying the heterogeneity of macromolecular machines by mass photometry. Nature Comm 11:1772. DOI 10.1038/s41467-020-15642-w.

  • Steinberg R, Origi A, Natriashvili A, Sarmah P, Licheva M, et al. (2020) Posttranslational insertion of small membrane proteins by the bacterial signal recognition particle. PLOS Biology 18(9): e3000874. https://doi.org/10.1371/journal.pbio.3000874

  • Thuenauer R, Landi A, Trefzer A, Altmann S, Wehrum S, Eierhoff T, Diedrich B, Dengjel J, Nyström A, Imberty A, Römer W. (2020) (accepted for publication) . The Pseudomonas aeruginosa lectin LecB causes integrin internalization and inhibits epithelial wound healing. mBio11:e03260-19

 

Publication Award 2020: Mirjam Bernhardt

 

2019

  • Breitsamer M, Stulz A, Heerklotz H, Winter G (2019) Do interactions between Protein and Phospholipids influence the release behavior from lipid-based exenatide depot systems? J. Pharm. Biopharm. 142, 61–69. DOI 10.1016/j.ejpb.2019.06.007.

  • Burschel S, Kreuzer Decovic D, Nuber F, Stiller M, Hofmann M, Zupok A, Siemiatkowska B, Gorka M, Leimkühler S and Friedrich, T (2019) Iron-Sulfur Cluster Carrier Proteins Involved in the Assembly of Escherichia coli NADH:ubiquinone oxidoreductase (complex I). Microbiol. 111, 31-45. DOI 10.1111/mmi.14137.

  • Ellenrieder L, Dieterle MP, Doan KN, Mårtensson CU, Floerchinger A, Campo, ML, Pfanner, N and Becker, T (2019) Dual role of mitochondrial porin in metabolite transport across the outer membrane and protein transfer to inner membrane. Cell73, 1056-1057.

  • Gnandt D  and Koslowski T (2019) Long-range electron-electron interaction and charge transfer in protein complexes: a numerical approach. Chem. Chem. Phys.21, 18595-18604. DOI 10.1039/C9CP03141C.

  • Kalel V, Li M, Gausmann S, Delhommel F, Schäfer A, Tippler B, Jung M, Maier R, Oeljeklaus S, Schliebs W, Warscheid B, Sattler M, Erdmann R (2019) Evolutionary divergent PEX3 is essential for the glycosomes biogenesis and survival of the trypanosomatid parasites. Biophys. Acta Mol. Cell. Res., 1866:118520.

  • Li M, Müller C, Fröhlich K, Gorka O, Zhang L, Groß O, Schilling O, Einsle O, Jessen-Trefzer C. (2019) Detection and characterization of a mycobacterial L-arabinofuranose ABC-transporter identified with a rapid lipoproteomics protocol. Cell Chem. Biol.26, 252-262. DOI: 10.1016/j.chembiol.2019.03.002.

  • Marckmann D, Trasnea P-I, Schimpf J, Winterstein C, Andrei A, Schmollinger S, Blaby-Haas CE, Friedrich T, Daldal F and Koch HG (2019) The cbb3-type cytochrome oxidase assembly factor CcoG is a widely distributed novel cupric reductase. Natl. Acad. Sci. USA, 116, 21166-21175. DOI 10.1073/pnas.1913803116.

  • Mårtensson CU, Priesnitz C, Song J, Ellenrieder L, Doan KN, Boos F, Floerchinger A, Zufall N, Oeljeklaus S, Warscheid B and Becker T (2019) Mitochondrial protein translocation-associated degradation. Nature569, 679-683.

  • Origi A, Natriashvili A, Knüpffer L, Fehrenbach C, Denks K, Asti R, Koch H-G (2019) Yet another role for the bacterial ribosome. Cell6, 524-526.

  • Poveda-Huertes D, Matic S, Marada A, Habernig L, Licheva M, Myketin L, Gilsbach R, Tosal-Castano S, Papinski D, Mulica P, Kretz O, Kücükkose C, Taskin A, Hein L, Kraft C, Büttner S, Meisinger C, and Vögtle FN (2019). An early mtUPR: Redistribution of the nuclear transcription factor Rox1 into mitochondria protects against intramitochondrial proteotoxic aggregates. Cell77, 180-188. DOI 10.1016/j.molcel.2019.09.026

  • Priesnitz C, Pfanner N, Becker, T (2019). Studying protein import into mitochondria. Methods in Cell Biology, 155, ISSN 0091-679X. DOI 10.1016/bs.mcb.2019.11.006

  • Schulte M, Frick K, Gnandt E, Jurkovic S, Burschel S, Labatzke R, Aierstock K, Fiegen D, Wohlwend D, Gerhardt S, Einsle O and Friedrich T (2019) A mechanism to prevent production of reactive oxygen species by Escherichia colirespiratory complex I. Nature Commun. 10:2551, DOI 10.1038/s41467-019-10429.

  • Theßeling A, Rasmussen T, Burschel S, Wohlwend D, Kägi J, Müller R, Böttcher B, and Friedrich T (2019) Homologous bd oxidases share the same architecture but differ in mechanism. Nature Commun.10: 5138. DOI: 10.1038/s41467-019-13122-4.

  • Utz M, Andrei A, Milanov M, Trasnea,PI, Marckmann,D, Daldal F and Koch H.G.(2019) The Cu chaperone CopZ is required for Cu homeostasis in Rhodobacter capsulatus and influences cytochrome cbb3 oxidase assembly.  Microbiol.111, 764-783. DOI 10.1111/mmi.14190.

  • Wilhelm I, Levit-Zerdoun E, Jakob J, Villringer S, Frensch M, Übelhart R, Landi A, Müller P, Imberty  A, Thuenauer  R, Claudinon J, Jumaa H, Reth M, Eibel H, Hobeika E, Römer W (2019) Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins. Signal.12(571) 7194. DOI 10.1126/scisignal.aao7194

  • Zhang L, Wüst A, Prasser B, Müller C, and Einsle O (2019) Functional assembly of nitrous oxide reductase provides insights into copper site maturation. Natl. Acad. Sci. USA116, 12822-12827.

 

Publication award 2019: Christoph Mårtensson

 

2018

  • Aufschnaiter A, Kohler V, Walter C, Tosal-Castano S, Habernig L, Wolinski H, Keller W, Vögtle FN & Buettner S (2018). The Enzymatic Core of the Parkinson’s Disease-Associated Protein LRRK2 Impairs Mitochondrial Biogenesis in Aging Yeast. Frontiers in Molecular Neuroscience. 11. 10.3389/fnmol.2018.00205. 

  • Böttinger L, Mårtensson CU, Song J, Zufall N, Wiedemann N and Becker T(2018) Respiratory chain supercomplexes associate with the cysteine desulfurase complex oft he iron-sulfur cluster assembly machinery. Mol. Biol. Cell 29, 776-785.

  • Dannenmaier S, Stiller S, Morgenstern M, Lübbert P, Oeljeklaus S, Wiedemann N, Warscheid B (2018) Complete native stable isotope labeling by amino acids of Saccharomyces cerevisiae for global proteomic analysis, Anal Chem, 90:10501-10509.

  • Drechsler C, Markone  M, Choi JY, Frieling N, Fiedle  S, Voelker DR, Schubert R, Heerklotz H (2018) Preparation of Asymmetric Liposomes Using a Phosphatidylserine Decarboxylase, Biophys J, 11,  1509-1517.

  • Gnandt D, Na S, Koslowski T (2018) Simulating biological charge transfer: continuum dielectric theory or molecular dynamics?, Biophysical Chemistry 241, 1.

  • Hoeser J, Gnandt E & Friedrich T (2018): Low cost, microcontroller based heating device for multi-wavelength differential scanning fluorimetry. Sci. Rep. 8:1457 DOI:10.1038/s41598-018-19702-6.

  • Kravic B, Harbauer AB, Romanello V, Simeone L,  Vögtle FN, Kaiser T, Straubinger M, Huraskin D, Böttcher M, Cerqua C, Martin ED, Poveda-Huertes D, Buttgereit A, Rabalski AJ, Heuss D, Rudolf R, Friedrich O, Litchfield,D, Marber M, Salviati L, Mougiakakos D, Neuhuber W, Sandri M, Meisinger C, and Hashemolhosseini S (2018) In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy 14, 311-335.

  • Na S,  Jurkovic T,  Friedrich T,  Koslowski T (2018) Charge transfer through  a fragment of the respiratory complex I and its regulation: an atomistic simulation approach, Phys.Chem.Chem.Phys., 20, 20023.

  • Na S, Steinbrecher T, Koslowski T (2018) Thermodynamic integration network
approach to ion transport through protein channels: perspectives and
limits, J. Comp. Chem. 39, 2539-2550.

  • Opaliński Ł, Song J, Priesnitz C, Wenz LS, Oeljeklaus S, Warscheid B, Pfanner N and Becker T (2018) Recruitment of cytosolic J-proteins by TOM receptors promotes mitochondrial protein biogenesis. Cell Rep. 25, 2026-2043.

  • Pflüger T, Hernández CF, Lewe,P, Frank F, Mertens H, Svergun D, Baumstark MW, Lunin, VY, Jetten,  MSM and Andrade SLA (2018) Signaling Ammonium Across Membranes Through an Ammonium Sensor Histidine Kinase, Nature Commun, 9, 164.

  • Priesnitz C and Becker T (2018) Pathways to balance mitochondrial translation and protein import. Genes Dev. 32, 1285-1296.

  • Ribeiro JP, Villringer S, Goyard D, Coche-Guerente L, Höferlin M, Renaudet O, Römer W*, Imberty  A* (2018) Tailor-made Janus lectin with dual avidity assembles glycoconjugate multilayers and crosslinks protocells. Chem Sci. 9: 7634-41 * corresponding author

  • Schwarzer P, Wunsch-Palasis J, Bechthold A, Paululat T (2018) Biosynthesis of rishirilid B. Antibiotics (Basel) 7: 20-28.

  • Steinberg R, Knüpffer L, Origi A, Asti R and Koch HG (2018) Co-translational protein targeting in bacteria. FEMS Microbiol. Lett. 365(11): 10.1093 Thematic Series on Bacterial Protein Export.

  • Trasnea PI, Andrei A, Markmann D, Utz M, Khalfaoui-Hassani B, Selamoglu N, Daldal F and Koch HG (2018) A copper relay system involving two periplasmic chaperones drives cbb3 type cytochrome c oxidase biogenesis in Rhodobacter capsulatus. ACS Chemical Biology 13, 1388-1397.

  • Villringer S, Madl J, Sych T, Manner C, Imberty A & Römer W (2018) Lectin-mediated protocell crosslinking to mimic cell-cell junctions and adhesion. Sci. Rep. 8:1932. DOI:10.1038/s41598-018-20230-6.

  • Walter C, Gonczarowska-Jorge H, Sickmann A, Zahedi RP, Meisinger C and Schmidt O.(2018) Advanced tools for the analysis of protein phosphorylation in yeast mitochondria. Anal. Biochem. 554, 23-27.

  • Yifrach E, Fischer S, Oeljeklaus S, Schuldiner M, Zalckvar E, Warscheid B (2018) Defining the mammalian peroxisomal proteome, Subcell Biochem, 89:47-66.

 

Publication award 2018: Chantal Priesnitz

 

2017

  • Denks K, Sliwinski N, Erichsen V, Borodkina B, Origi A and Koch HG (2017) The signal recognition particle contacts uL23 and scans substrate translation inside the ribosomal tunnel. Nature Microbiology, 2, 16265.

  • Dörner K, Vranas M, Schimpf J, Straub IR , Hoeser J and Friedrich T (2017) Significance of the [2Fe-2S] Cluster N1a for Electron Transfer and Assembly of Escherichia coli Respiratory Complex I. Biochemistry, 56, 2770-2778. Doi: 10.1021/acs.biochem.6b01058.

  • Gnandt E, Schimpf J, Harter, C, Hoeser J and Friedrich T (2017) Reduction of the off- pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD+ dissociation. Sci. Rep., 7:8754. DOI:10.1038/s41598-017-09345-4.

  • Gonsberg A, Jung S, Ulbrich S, Origi A, Ziska A, Baier M, Koch HG, Zimmermann R, Winklhofer KF, and Tatzelt J (2017) The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins. J. Bio. Chem. 292, 21383-21396.

  • Ilcu L, Röther W, Birke J, Brausemann A, Einsle O & Jendrossek D (2017) Structural and functional analysis of latex clearing protein (Lcp) provides insight into the enzymatic cleavage of rubber. Sci. Rep., 7, 6179.

  • Käser S, Willemin M, Schnarwiler M, Schimanski B, Poveda-Huertes D, Oeljeklaus S, Warscheid B, Meisinger C, and Schneider A (2017). Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei. PLoS Pathog. 13, e1006808.

  • Mårtensson C and Becker T (2017) Acylglycerol Kinase: Mitochondrial protein transport meets lipid biosynthesis. Trends Cell Biol. 27, 700-702.

  • Mårtensson CU, Doan KN and Becker T (2017) Effects of lipids on mitochondrial functions. Biochim Biophys Acta. 182, 102-113.

  • Morgenstern M, Stiller SB, Lübbert P, Peikert CD, Dannenmaier S, Drepper F, Weill U, Höß P, Feuerstein R, Gebert M, Bohnert M, van der Laan M, Schuldiner M, Schütze C, Oeljeklaus S, Pfanner N, Wiedemann N, and Warscheid B (2017) Definition of a high-confidence mitochondrial proteome at quantitative scale. Cell Rep, 19(13):2836-2852.

  • Na S, Bauß A, Langenmaier M, Koslowski T (2017) Thermodynamic Integration Network Study of Electron Transfer: from Proteins to Aggregates, PCCP, 19, 18938.

  • Schummer A, Fischer S, Oeljeklaus S, Warscheid B (2017) Study of peroxisomal protein phosphorylation by functional proteomics, Methods Mol Biol, 1595:267-289. 

  • Zheng S, Eierhoff T, Aigal S, Brandel A, Thuenauer R, de Bentzmann S, Imberty A, Römer W (2017) The Pseudomonas aeruginosa lectin LecA triggers host cell signalling by glycosphingolipid-dependent phosphorylation of the adaptor protein CrkII. Biochimica et Biophysica Acta - Molecular Cell Research. 1864(7): 1236-45.

 

Publication award 2017: Sehee Na