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Unusual ammonium transporters

Two PhD positions in the the Andrade group, located at the Institute for Biochemistry, Faculty of Chemistry and Pharmacy (http://www.biophysics.uni-freiburg.de), which will focus on investigating the structure and function of ammonium transport proteins.

Applications are welcome at any time and will be accepted until all positions are filled. Women are particularly encouraged to apply.

Abstract

We look for highly motivated and creative students with strong interest in ion transport membrane proteins. We offer an excellent opportunity to engage into an exciting PhD project that combines biochemical, biophysical and structural biology tools to investigate how ammonium transport (Amt) proteins function in ion transport and signal transduction events, in the context of a dynamic and enthusiastic work environment, with state-of-the-art equipment and various chances for national and international scientific collaborations.

The selected students will typically clone, purify, reconstitute protein in proteoliposomes, carry out electrophysiology experiments, characterize proteoliposomes by freeze-fracture TEM or cryo-EM and solve the three-dimensional structure of interesting variants. Preference will be given to students that had previous experience with protein purification and (eventually) electrophysiology techniques.

 

For further information, please contact Prof. Dr. Susana Andrade.

Applications should be sent to rtg2202@bio.chemie.uni-freiburg.de

 

 

Single molecule imaging

Ulbrich Laboratory, University of Freiburg, Germany

Single Molecule Microscopy – Superresolution Imaging – Biophysics of Membrane Proteins

A PhD position in single molecule biophysics is available in the laboratory of Dr. Maximilian Ulbrich at the University of Freiburg. We are looking for an independent and motivated individual who holds a M.Sc. degree in Biology, Physics, Chemistry or a related discipline. 

Abstract

The goal of this project is to resolve the assembly of protein complexes in biological membranes by single molecule imaging in living cells, and advance the related technical approach. Our laboratory is primarily interested in the assembly of neuronal receptors like the AMPA receptor and GPCRs, and the dynamics during signaling processes of receptor tyrosine kinases. The work includes wet lab biology (cloning, biochemistry, cell culture), instrumentation (assembly of custom single-molecule microscopes), and programming to control equipment and evaluate results. 

Ideally, applicants should bring enthusiasm for science, creativity, technical and programming skills, as well as experience in microscopy, molecular biology and/or biochemistry

Please submit your application electronically to: max.ulbrich@bioss.uni-freiburg.de